Tag: Differential diagnosis of pruritus

  • Systemic Causes of Pruritus (Itching)

    The main systemic causes of itching are: Cholestasis Uremia Pregnancy-related problems Lymphoproliferative (especially systemic mastocytosis) and hematopoietic disorders, including iron deficiency anemia Endocrinal problems such as hypothyroidism and diabetes mellitus Drug side effects, such as opioids and drugs which cause cholestasis. Allergic reactions Therefore, in the absence of primary skin findings, a basic workup for itching might…