Mnemonic for Side Effects of Antimycobacterial Agents

Scanning electron micrograph of Mycobacterium tuberculosis bacteria

Here is a mnemonic that will help you remember the side effects of  antimycobacterial agents: Rifampin cause Red discoloration of urine and tears, which can lead to patient anxiety and ruined contact lenses. Patients should be counseled about this ahead of time and should be advised not to wear contact lenses while being treated with … Read more

Book Review: Acing the Hepatology Questions on the GI Board Exam

Acing the Hepatology Questions on the GI Board Exam

Acing the Hepatology Questions on the GI Board Exam, the Ultimate Crunch-Time Resource by Brennan M.R. Spiegel (2012)  is an excellent choice for anyone who is looking for a solid understanding of hepatic pathology, diagnostics and therapeutics. The book is vignette-driven and features most of the important and high-yield hepatic conditions including acetaminophen overdose, viral hepatitides, and dozens … Read more

Toxic Hepatitis and Jaundice

Here are some important causes of toxic hepatitis and jaundice (notorious ones are in bold): Hepatocellular (elevated ALT and AST only): acarbose, acetaminophen, allopurinol, amiodarone, aspirin (in Reye’s syndrome), baclofen, bupropion, fluoxetine, HAART drugs, isoniazid, ketoconazole, lisinopril, losartan, methotrexate, NSAIDs, omeprazole, paroxetine, pyrazinamide, rifampin, risperidone, sertraline, statins, tetracyclines, trazodone, trovafloxacin, valproic acid, Vitamin A. Herbals … Read more

An Internal Medicine Approach to Abnormal Liver Chemistry Studies

Causes of liver damage include: Toxic Acute alcoholic hepatitis (fever, leukocytosis, abnormal liver chemistry studies) acetaminophen Amanita poisoning (history of mushroom ingestion) Other drugs Infectious Viruses HAV (food-related outbreak with a relatively short incubation period) HBV HCV HEV (Pregnant patient from Southeast Asia with oro-fecally transmitted fulminant hepatitis with a very long (8 week) incubation period) CMV (teenager … Read more