Aortic Dissection: When to Suspect it

Aortic Dissection

Suspect an aortic dissection in patients with chest pain plus any of the following: New neurological problems Anterior spinal artery infarction with loss of motor function and loss of sensation (with preserved position and vibratory senses) Oculosympathetic paresis, or Horner syndrome, with miosis, ptosis, and anhidrosis A painful Horner’s is a dissection until proven otherwise Acute … Read more

Teach Yourself Laboratory Medicine!

Clinician's Guide to Laboratory Medicine Pocket

Laboratory medicine is one of the core competencies you must master if you want to become a superstar diagnostician within the span of one lifetime or less.     Here is my proposed “curriculum” for mastery of laboratory medicine: Urinalysis and Body Fluids, 5e, by Susan King Strasinger – a great book. Clear, fluid and … Read more

How to Solve Triple Acid-Base Problems Quickly in Your Head

Aspirin spilling from bottle

Introduction You can solve triple acid-base problems with basic arithmetic and straightforward logic. As an example, let’s work through the following rather classic triple acid-base problem: An afebrile, atraumatic 26-year-old male with no past medical history is brought to the emergency department because of a three hour history of altered mental status, vomiting and vertigo. The physical examination is … Read more

Disseminated Intravascular Coagulation (DIC)

Rattlesnake

Introduction Disseminated Intravascular Coagulation (DIC) is a very serious and life-threatining coagulation cascade disorder that is sometimes seen in patients with severe physiologic stressors such as sepsis, obstetric complications (for example, placental abruption, retained products of conception, or amniotic fluid embolization) or major tissue injury from trauma, burns, shock, snake bites, or malignancy (for example, acute promyelocytic leukemia). … Read more

How to Spot a Falsely Normal Anion Gap

Introduction A high anion gap metabolic acidosis can be a very dangerous acid-base abnormality. The “gap” itself is just a number – it isn’t harmful per se. Rather, the danger is from the acidosis and from the process that is generating the abnormal and excessive organic acid load. The most common screening test for high anion gap … Read more

How to Become a Superstar Diagnostician Within the Span of One Lifetime or Less

Aequanimitas

To become a great diagnostician, you need to excel in six different diagnostic modalities: (1) history-taking, (2) physical examination, (3) laboratory medicine, (4) medical imaging (including point-of-care ultrasonography), (5) electrocardiography, and (6) bedside diagnostic procedures. History-taking The two most important components of history-taking are knowing what to ask and how to ask questions. Prepare and perfect scripted questions for … Read more

Book Review: Illegal Drugs, A Complete Guide to Their History, Chemistry, Use, and Abuse

Illegal Drugs

You can judge this book by its title. Illegal Drugs: A Complete Guide to Their History, Chemistry, Use, and Abuse (2003) by Paul M. Gahlinger MD is, in fact, an extremely comprehensive treatment of both illegal and legal psychoactive substances, including their history, law, chemistry, processing and distribution, metabolism, neuroscience, medical management, linguistics, folklore, and popular culture. Hundreds of … Read more